About Us

Cyrex Laboratories is an advanced clinical laboratory specializing in a functional approach to assess environmentally-induced autoimmunity.

The newest test from Cyrex, The Lymphocyte MAP™ measures the integrity of the immune system at the cellular level, enabling practitioners to classify their patients' immunotype or their immune identity. Immunotypes can identify weakness or imbalance in the immune fitness of patients and will enable practitioners to design immunotype-specific immune rejuvenation plans to prevent or halt the progression of the many immune disorders that affect 1 out of 3 Americans.

Cyrex offers environmental trigger (foods, chemicals and pathogens), barrier permeability (intestinal and blood-brain) and multiple organ self-tissue antibody testing. These key assessments for a variety of antigens, can be used for the early detection and monitoring of today's complex autoimmune conditions. Through continuous collaboration with leading experts in medical research and clinical practice, Cyrex develops innovative tests that address the cross-connections between the body's immune, gastrointestinal and neurological systems and provides tools for the evaluation of complex disorders.

Since opening in 2011, Cyrex has been the functional medicine practitioner's go-to lab for functional immunology testing which helps practitioners recover, and maintain quality of life for their patients with cutting edge tests, using the most advanced testing methods available.

Meet The Team

Interim CEO - Mark McDonough

Mark McDonough serves as Interim CEO of Cyrex Labs as of May 2024. Prior to this, he served in several private and public company CEO roles to include PierianDx and CombiMatrix, a publicly held molecular diagnostics company performing DNA-based testing services for reproductive health, oncology, and developmental disorders.

As CEO of CombiMatrix, from 2013-2017, Mark led a dramatic turnaround of a struggling company with a precise focus on high margin growth coupled with disciplined cost reduction. CombiMatrix revenue grew 300% over his tenure and achieved profitability. At PierianDx, he led 40% revenue growth in back-to back years leading to significant Private Equity interest. Mark has also held executive and management positions with US LABS (acquired by LabCorp) and Ventana Medical Systems (acquired by Roche). Mark is the Founder and CEO of McDonough Leadership Advisors, a private consulting firm specializing in company, culture, and commercial growth expertise.

Sadi, Koksoy, Ph.D, DVM - Technical Supervisor

Dr. Koksoy is the founder of the Clinical and Research Immunology and Flow Cytometry Core Laboratory at Akdeniz University, consisting of both Clinical and Research divisions. There he developed and validated various state-of-the-art flow cytometric and immunological tests and protocols that meet national and international regulatory standards for the immunologic assessment of transplant patients, diagnosing immunodeficiencies, autoimmune diseases, hematologic malignancies, and certain infections. He also served as the Associate Director of the Histocompatibility and Immunogenetics laboratory, which is a part of one of the largest transplantation centers in Europe.

Dr. Koksoy served as a Professor of Medical Microbiology and Immunology at Akdeniz University, School of Medicine. He received his MSc and PhD degrees in the fields of Microbiology and Immunology from Ohio State University, and his Doctor of Veterinary Medicine, from Ankara University, Turkey. He has authored/co-authored more than 50 SCI-indexed papers in scientific journals.

Cyrex Laboratories' Advisors

Chief Scientific Advisor - Aristo Vojdani, Ph.D., M.Sc., C.L.S.

Dr. Aristo Vojdani obtained his Ph.D. in the field of microbiology and clinical immunology with postdoctoral studies in tumor immunology at UCLA. Dr. Vojdani's ongoing research, spanning a 40-year career, focuses on the role of environmental factors, such as toxic chemicals, infections and dietary proteins and peptides in complex diseases. An owner of 15 U.S. patents for laboratory assessments, he has published 120 peer-reviewed articles in scientific journals. Dr. Vojdani is CEO and technical director of Immunosciences Lab., Inc. in Los Angeles, CA, a member of the editorial board of four scientific journals, and a guest editor of six journals.

Copy of Cyrex Laboratories' Advisors

Mark R. Engelman- Director Of Clinical Consulting- M.D, FSCM, FAARM, ABAARM

Dr. Engelman received his BS undergraduate degree from Ohio State University. He received an M.D, degree from Ohio State College of Medicine. He was a resident in Internal Medicine at St. Joseph's Hospital and Medical Center, Phoenix, Arizona. Dr. Engelman was an Emergency Department staff Physician at St. Joseph's for 23 years and served as Emergency Department Director for 22 years. He was Board Certified in Emergency Medicine. Dr. Engelman became fascinated about Integrative Functional Medicine. He has earned a Fellowship in Stem Cell Medicine Certification and Advanced Fellowship in Integrative Functional Medicine. He is the Founder and Director of Engelman Health Institute in Phoenix and has utilized Cyrex Labs in his practice.

Chad Larson, NMD, DC, CCN

Dr. Larson holds a Doctor of Naturopathic Medicine degree from Southwest College of Naturopathic Medicine and a Doctor of Chiropractic degree from Southern California University of Health Sciences, graduating with honors. He is a Certified Clinical Nutritionist and a Certified Strength and Conditioning Specialist.

His practice integrates naturopathic medicine with cutting-edge laboratory testing and diagnostic imaging. This integrative approach to medicine includes diet and nutritional counseling, prolotherapy, regenerative injection therapy (RIT), chiropractic manipulative therapy, bio-identical hormone balancing, intravenous (IV) nutritional therapy, and natural alternatives to prescription drugs.

He particularly pursues advanced developments in the fields of endocrinology, orthopedics, sports medicine, and environmentally induced chronic disease.

He has been featured on local and national radio and television programs discussing a broad range of health issues. Dr. Larson has been invited to lecture to a variety of groups from the U.S. Army Special Forces to executive leadership groups to universities and healthcare practitioners. He has published articles in various consumer and professional periodicals and has worked with the Research & Development departments of nutritional supplement companies. Dr. Larson also stays on the cutting edge of laboratory science as an advisor and consultant to Cyrex Laboratories.

Dr. Larson is Board Certified in both Naturopathic Medicine and Chiropractic.

Sam Sunshine, M.D.

Sam Sunshine, M.D., is a board-certified Family Medicine and Sports Medicine physician, as well as the founder of OC Sports and Wellness. After completing his undergraduate studies at Stanford University, he earned his medical degree from the University of Southern California. He then completed both his Family Medicine residency and Sports Medicine Fellowship at Kaiser Permanente - Fontana, California.

As the medical director of his direct primary care clinic, he emphasizes preventive and lifestyle medicine and employs the principles of functional medicine. His dedication to patient care has earned him the Physician of Excellence award from the Orange County Medical Association for eight consecutive years. For the last sixteen years, he has volunteered as a charge doctor for the Ironman World Championships. In October of 2022, he completed the Ironman in Kona, Hawaii.